STUDIES ON THE BACTERIAL PYROGENIC SUBSTANCES
نویسندگان
چکیده
منابع مشابه
Bacterial pyrogenic exotoxins as superantigens.
The recent discovery of the mode of interaction between a group of microbial proteins known as superantigens and the immune system has opened a wide area of investigation into the possible role of these molecules in human diseases. Superantigens produced by certain viruses and bacteria, including Mycoplasma species, are either secreted or membrane-bound proteins. A unique feature of these prote...
متن کاملObservations on the Production of Pyrogenic Substances by Rabbit and Human Leucocytes
1. The mechanism of release of a pyrogen from leucocytes has been studied in cells obtained from sterile rabbit peritoneal exudates and from rabbit blood. Attempts were made to induce human leucocytes-from blood-to release a pyrogen. 2. Rabbit leucocytes, kept below 4 degrees C., were not pyrogenic and did not release any pyrogen when disintegrated. Incubating such cells, in various media, at 3...
متن کاملStudies on the Effect of Certain Toxic Substances in Bacterial Cultures on the Movement of the Intestines
Following intravenous injection, filtrates of young cultures of B. paratyphosus B often produce marked diarrhea in rabbits. A study was made of the effect of these toxic filtrates on the motility of the small intestines of the rabbit. The observations were made on a segment of the small intestines in situ, and in the living animal. It was found that an immediate slight rise of tone of the longi...
متن کاملStudies on Bacillus Typhosus Toxic Substances
A phenomenon of local skin reactivity to B. typhosus culture filtrates is described in this report. The reactivity was induced by skin injections of the filtrate followed 24 hours later by an intravenous injection of the same filtrate. The local response consisted of severe hemorrhagic necrosis and was fully developed 4 to 5 hours after the second injection. About 78 to 79 per cent of the rabbi...
متن کاملStudies on Bacterial Localization
THE RESULTS OF GROSS AND MICROSCOPIC OBSERVATIONS AND SURVIVAL TESTS AFTER SUBCUTANEOUS INFECTION OF MICE WITH TYPE I PNEUMOCOCCI CAN BE SUMMARIZED AS FOLLOWS: Normal mice possessed no adequate means of protection against this organism. The bacteria disseminated freely through the tissue spaces in the presence of widespread inflammation, and were not ingested by significant numbers of host cell...
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ژورنال
عنوان ژورنال: The Japanese Medical Journal
سال: 1950
ISSN: 1884-281X
DOI: 10.7883/yoken1948.3.125